High expression of Twist is associated with tumor aggressiveness and poor prognosis in patients with renal cell carcinoma.

CONCLUSIONS: Twist plays important roles in tumor growth, progression, and survival in patients with RCC patients. Such pathological mechanisms are significantly associated with increased cancer cell proliferation, angiogenesis, MMP2 expression, and macrophage recruitment. These findings are important information for discussion of treatment and observation strategies in these patients. PMID: 25031735 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25031735?dopt=Abstract

Source: International Journal of Clinical and Experimental Pathology - July 19, 2014 Category: Pathology Authors: Ohba K, Miyata Y, Matsuo T, Asai A, Mitsunari K, Shida Y, Kanda S, Sakai H Tags: Int J Clin Exp Pathol Source Type: research