Body composition and ectopic lipid changes with biochemical control of acromegaly.

Conclusions: Acromegaly is characterized by insulin resistance and hyperinsulinemia but lower IHL, compared to age-, BMI- and sex-matched healthy controls. Biochemical control of acromegaly improves insulin resistance but leads to a less favorable anthropometric phenotype with increased IHL, abdominal adiposity and decreased muscle mass.
PMID: 28945897 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - September 18, 2017 Category: Endocrinology Authors: Bredella MA, Schorr M, Dichtel LE, Gerweck AV, Young BJ, Woodmansee WW, Swearingen B, Miller KK Tags: J Clin Endocrinol Metab Source Type: research