Chronic pain and adult hippocampal neurogenesis: translational implications from preclinical studies

Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

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Abstract Chronic pancreatitis is a complex and irreversible disease of the pancreas and is associated with significant morbidity and mortality. Nutrition deficiencies in chronic pancreatitis are common and can be atypical in nature. As such, the management of these deficiencies can be individualized for patients. The aim of this review is to discuss the components of nutrition deficiencies in chronic pancreatitis, their management, and the current areas of research that are being explored. The clinical guidelines of major national and international societies were analyzed for recommendations on the nutrition manag...
Source: Nutrition in Clinical Practice - Category: Nutrition Authors: Tags: Nutr Clin Pract Source Type: research
Publication date: Available online 19 September 2019Source: Arthroscopy TechniquesAuthor(s): Adnan Kasapovic, Yorck Rommelspacher, Martin Gathen, Davide Cucchi, Rahel Bornemann, Robert Pflugmacher, Sebastian G. WalterAbstractSpinal cord stimulation (SCS) is an evidence-based, reversible but invasive procedure for the treatment of chronic pain syndromes: for example, in patients with failed-back-surgery syndrome or complex regional pain syndrome. A more recent, similar technique uses high-frequency stimulation for SCS and follows a different mechanism of action that does not result in paresthesia. This Technical Note and vi...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
Publication date: Available online 19 September 2019Source: Brain, Behavior, and ImmunityAuthor(s): Yinghua Peng, Xiaozheng Zhang, Tianshu Zhang, Peter M. Grace, Hongyuan Li, Yibo Wang, Hang Li, Hongqian Chen, Linda R. Watkins, Mark R. Hutchinson, Hang Yin, Xiaohui WangAbstractThere is growing interest in drug repositioning to find new therapeutic indications for drugs already approved for use in people. Lovastatin is an FDA approved drug that has been used clinically for over a decade as a lipid-lowering medication. While lovastatin is classically considered to act as a hydroxymethylglutaryl (HMG)-CoA reductase inhibitor,...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Condition:   Chronic Pain Intervention:   Other: Neurofeedback Sponsors:   University of Manchester;   TIYGA Health Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusion: The patient was not treated with the routine therapy used in previously reported cases (curettage), suggesting that antibiotic therapy should be considered before employing surgical interventions for XO. PMID: 31528142 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research
Conclusion: Recurrent Takotsubo cardiomyopathy involving different anatomic regions of the left ventricle is a rare phenomenon yet appears to be similar to typical Takotsubo cardiomyopathy in presentation and hospital course. Chronic therapy with beta blockers and angiotensin-converting enzyme inhibitors did not prevent a recurrence in this patient, suggesting that optimum treatment needs to be determined. Takotsubo cardiomyopathy affecting different myocardial segments may recur in the same patient, implying that the adrenoceptor distribution theory needs further refinement. PMID: 31528138 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research
(NEW YORK) — More than 500 people have been diagnosed with vaping-related breathing illnesses, but the cause remains unknown, U.S. health officials said Thursday. An eighth death was also reported. Meanwhile, the Food and Drug Administration revealed that its criminal investigations unit started tracking leads early on, as cases pointed to black market vaping products. The agency’s tobacco director, Mitch Zeller, stressed that it is not interested in prosecuting individuals who use illegal products but is lending a hand because of the unit’s “special skills.” The Centers for Disease Control an...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime vaping Source Type: news
In conclusion; the present study provides a variety of dynamic and isometric exercises; where muscle activity values and tolerability can be used as guide to design evidence-based exercise programs for outpatients with NSCLBP.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Case submitted by Alexis Cates, written by Pendell MeyersA middle aged man with history of HTN, DM, and VSD repair at age 6, presented to the ED with chest pain and diaphoresis while exercising.Here is his initial ECG:What do you think?Hopefully this is too easy for most readers, but it it shows a massive, obvious inferoposterior OMI, in the setting of sinus tachycardia with RBBB and LPFB. It may be too easy for you, but there is a very valuable teaching point for you as you spread ECG knowledge to your group, your residents, your learners.Over the past 3 years I have shown this ECG and many similar ones to many residents ...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
The next generation of doctors will start their careers at a time when physicians are feeling pressure to limit prescriptions for opioid painkillers.Yet every day, they'll face patients who are hurting from injuries, surgical procedures or disease. Around 20% of adults in the U.S. live with chronic pain.That's why some medical students felt a little apprehensive as they gathered recently for a mandatory, four-day course at Johns Hopkins University in Baltimore — home to one of the top medical schools in the country.The subject of the course? Pain."I initially was a bit scared and I guess a bit wary comin...
Source: Psychology of Pain - Category: Anesthesiology Source Type: blogs
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