Association between ovarian endometrioma and ovarian reserve.

Association between ovarian endometrioma and ovarian reserve. Front Biosci (Elite Ed). 2018 Jan 01;10:92-102 Authors: Kitajima M, Khan KN, Harada A, Taniguchi K, Inoue T, Kaneuchi M, Miura K, Masuzaki H Abstract Endometrioma is one of the main pathologies of endometriosis, though its pathogenesis still remains enigmatic. Ovarian reserve is defined as the number and quality of the follicles left in the ovary at any given time. The cause of infertility in women with endometriosis is multifactorial. Diminished ovarian reserve is major concern in women with endometriosis-associated infertility. Cystectomy for endometriomas could negatively impact on post-operative ovarian reserve. Some women had surgery for endometriomas suffer from poor ovarian response, which directly affects treatment results. In addition, endometriomas themselves may be a cause of diminished ovarian reserve. Destruction of normal histological structure in ovarian cortex may affect dormancy of primordial follicles. Therefore, determination of ovarian reserve may serve as an important role in the management of reproductive health of women with endometriosis. Although the knowledge on the physiology of follicular development and mechanism of maintenance of ovarian reserve are rapidly accumulating, results obtained by ovarian reserve testing after surgery should be carefully evaluated according to the time-points and selected test. Further investigation on this issue is warranted. PMID: 2...
Source: Frontiers in Bioscience - Elite - Category: Biomedical Science Tags: Front Biosci (Elite Ed) Source Type: research

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Authors: Lee D, Kim SK, Lee JR, Jee BC Abstract Endometriosis is a common inflammatory disease in women of reproductive age and is one of the major causes of infertility. Endometriosis causes a sustained reduction of ovarian reserve through both physical mechanisms and inflammatory reactions, which result in the production of reactive oxygen species and tissue fibrosis. The severity of endometriosis is related to ovarian reserve. With regard to infertility treatment, medical therapy as a neoadjuvant or adjuvant to surgical therapy has no definite beneficial effect. Surgical treatment of endometriosis can lead to ov...
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Conclusions: This study provides the first evidence that a personality dimension with many prognostic implications may be altered in women with endometriosis. Our findings highlight the importance of a broader understanding of this condition, treating this disorder from a biopsychosocial perspective and suggests the need for non-medical attention within a multidisciplinary team. PMID: 32081052 [PubMed - as supplied by publisher]
Source: Journal of Psychosomatic Obstetrics and Gynaecology - Category: OBGYN Tags: J Psychosom Obstet Gynaecol Source Type: research
ConclusionsBeyond our expectations, infertile endometriosis women showed to feel more understood and supported than the others. Possible explanations and implications are discussed.RésuméObjectifsLe but de cette étude était d’explorer si les femmes atteintes d’infertilité liée à l’endométriose avaient des scores psychologiques, sexuels et relationnels moins satisfaisants par rapport à l’endométriose sans infertilité.MéthodesSoixante-onze femmes atteintes d’endométriose (32 avec infertilité as...
Source: Sexologies - Category: Sexual Medicine Source Type: research
ConclusionWe report a strong linkage between a novel MIF haplotype and endometrioma. This association is consistent with expression data at both transcript and protein levels suggesting the −173C/G promoter as a critical factor.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
ConclusionsWomen with endometrioma should be counseled about oocyte cryopreservation for FP before surgery. The optimal number of oocytes for cryopreservation can be secured by repeated oocyte retrieval.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionThe mural fibrosis seen in the cystic wall reflects unrecognized ovarian stromal fibrosis induced by the fibrogenic effects of endometriosis. This process may play a potential role in provoking infertility in patients with endometriosis, and could be reversed by administrating the LH-inhibiting regimens.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
AbstractDeeply infiltrative endometriosis (DIE) is a common gynecologic disease affecting women of reproductive age and often causing chronic pelvic pain and infertility. Clinical treatment options and preventive actions are ineffective due to the lack of knowledge about the etiology of DIE. Surgical treatment is currently the only alternative to eradicate the disease. Diagnostic imaging plays a crucial role for surgical planning and postoperative evaluation. Transvaginal sonography (TVS) with a dedicated protocol and magnetic resonance imaging (MRI) can be used to evaluate recurrent disease. Extensive pelvic surgery may c...
Source: Abdominal Imaging - Category: Radiology Source Type: research
ConclusionsThe results suggest that the inflammatory milieu of ovarian endometriosis is strongly localized and has a more modestly systemic effect. The effect of endometriomas on infertility, however, cannot be entirely explained by increased inflammation.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
Conclusions: The three most relevant disorders mentioned were polycystic ovary syndrome, endometriosis and vulvodynia. These diseases cause several impacts on the lives of women, because they feel stigmatized and limited in their daily life and sexuality, and the diagnosis of these diseases takes too much time. Governments should better redistribute the financing of women’s health and allocate resources to specialized centers.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
CONCLUSION: Self-reported DxE is prevalent among Canadian women and is associated with a substantial symptomatic burden. The 5.4-year diagnostic delay reported here indicates an important unmet need for more timely diagnosis of endometriosis in Canada. PMID: 32001176 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
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