Radioresistance of the breast tumor is highly correlated to its level of cancer stem cell and its clinical implication for breast irradiation.

CONCLUSIONS: Percentage of CSCs strongly correlated to overall tumor radioresistance. This observation suggested potential individualized radiotherapy to account for heterogeneous population of CSCs and their distinct radiosensitivity for breast cancer.
PMID: 28923575 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 15, 2017 Category: Radiology Authors: Qi XS, Pajonk F, McCloskey S, Low DA, Kupelian P, Steinberg M, Sheng K Tags: Radiother Oncol Source Type: research