Impact of Placental Growth Factor on the First Day of Admission in Patients with Acute Decompensated Heart Failure

Background: Significance of placental growth factor (PlGF) in acute decompensated heart failure (ADHF) was not clear. Methods: We have studied consecutive 436 patients with ADHF admitted to our department from 2011 through 2014. Of 436 patients, 271 patients measured PlGF levels on day 1 were studied. The primary endpoints were all-cause death and cardiovascular (CV) death.Results: We divided into two groups according to PlGF quartiles. Crude Kaplan-Meier curves revealed that high PlGF group (quartile 4; ≥14.1 pg/ml) had worse prognosis than low PlGF group (quartile 1–3;

Source: Journal of Cardiac Failure - September 20, 2017 Category: Cardiology Authors: Yasuki Nakada, Rika Kawakami, Satomi Ishihara, Tomoya Ueda, Hiroyuki Kawata, Hiroyuki Okura, Yoshihiko Saito Source Type: research