Combination of High-Dose Methylprednisolone and Defibrotide for Veno-Occlusive Disease in Pediatric Hematopoietic Stem Cell Transplant Recipients

• Addition of high-dose steroids to defibrotide improves VOD response after HSCT• Addition of high-dose steroids to defibrotide in patients with VOD improves OS• Brief high-dose steroid pulse is beneficial and low risk therapy for VOD
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research