E-cigarettes linked to increased arterial stiffness, blood pressure and heart rate in humans
(European Lung Foundation) New research, to be presented at the European Respiratory Society International Congress, has shown for the first time that e-cigarettes with nicotine cause a stiffening of the arteries in humans. This has important implications for the use of e-cigarettes, as arterial stiffness is associated with an increased risk of heart attacks and strokes in later life.
We read the meta-analysis by Phan et al,1 “Endovascular thrombectomy alone versus combined with intravenous thrombolysis,” with enthusiasm. In their study, the authors address one of the central uncertainties relevant to the current practice of stroke treatment: What is the added value of pretreatment with intravenous thrombolysi s to eligible patients treated with mechanical thrombectomy? While recognizing the study limitations, the authors present the following main results: 1) A strong trend towards favorable functional outcomes 2) without a change in mortality or 3) in the proportion of symptomatic in...
The process by which the brains of ground squirrels are protected against low oxygen during hibernation could lead to a new treatment for ischemic stroke.
SCIENTISTS have announced a ‘real advance’ in combating high blood pressure, a condition that affects millions and leads to heart attacks and strokes.
ConclusionDespite the proven causative relationship between severe HT and neurological deterioration in human stroke, rt-PA-triggered HT in mouse MCAo does not contribute to neurological deficit or simulate sICH. Model limitations, such as the long duration of occlusion required, the type of HT achieved and the timing of deficit assessment may account for this mismatch. Our results further suggest that blockade of LDL receptors improves stroke outcome irrespective of rt-PA, blood –brain barrier breakdown and HT.
AimsWe sought to assess the risk of major adverse cardiovascular events (MACE) by utilizing high‐sensitivity C‐reactive protein (hsCRP) level and low‐density lipoprotein cholesterol (LDL‐C) in patients with type 2 diabetes and recent acute coronary syndrome. Materials and methodsStudy participants enrolled in the EXAMINE trial (Clinical trials registration number: NCT00968708) and were stratified by baseline hsCRP levels (3 mg/L). They were also sub‐divided into 4 groups according to baseline hsCRP (≤3 or>3 mg/L) and achieved LDL‐C (
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.firstname.lastname@example.org Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Prompt treatment of a mini-stroke could reduce the likelihood of having a full-blown stroke by roughly 80 percent, according to a new report.
Jeremy N. Pulvers, John D. G. Watson
Condition: Stroke Intervention: Other: Enhanced Treadmill Training Sponsor: University of Strathclyde Not yet recruiting