MassDevice.com +5 | The top 5 medtech stories for September 6, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters. 5. Did Congress just kill medical device innovation? The Medical Device User Fee Amendments bill that Congress passed this year is more than an FDA fees hike for device companies; it could inhibit innovation, says Michael Drues, a regulatory consultant based outside Boston. That’s because MDUFA 2017 includes new user fees – about $23,000 for small companies and $93,000 for large companies – for requests for de novo device classifications. Drues, who has worked with both device companies and FDA, has clients speeding up de novo applications to get them turned in before the fees take effect on Oct. 1. Read more 4. Pulmatrix licenses inhaled COPD drug to Vectura Pulmatrix said today that it licensed its inhaled COPD drug to Vectura. The PUR0200 compound combines tiotropium bromide and Pulmatrix’s iSperse drug-delivery technology. Vectura plans to use its dry powder inhaler device to deliver PUR0200, the company said. Read more 3. Boston Scientific wins FCA whistleblower suit over Cognis CRT-Ds, Teligen ICDs Boston Scientific has prevailed in dismi...
The guideline-recommended FEV1:FVC cutoff of lower than 0.70 accurately diagnoses clinically significant COPD and predicts COPD-related hospitalization and death, a study found.Medscape Medical News
Conclusion: These findings suggest that EM increased SIRT1, leading to acetylation/expression of NF- κB, and thereby decreasing cigarette smoke-driven NF-κB-dependent proinflammatory cytokine.Pathobiology
Conclusion: Results concerning muscle dysfunction in smokers are divergent, since some studies have shown worse results in a variety of muscle strength variables in smokers compared with nonsmoking controls, whereas other studies have not. Moreover, there is rather preliminary evidence indicating worse muscle dysfunction and lower CSA in patients with mild COPD in comparison with healthy (or non-COPD) smokers.
Conclusion: Activities of daily living lead to oxygen desaturation and high ventilatory demand. London Chest Activity of Daily Living Scale reflected 33% and SGRQ reflected 67% of the functional limitation during ADL simulation, such as dyspnea and the metabolic demand during ADL.
Conclusion. Our study identifies the various factors associated with a lower likelihood of RTW at 3 months after cervical spine surgery in the non-worker's compensation setting. This information provides expectations for the patient and employer when undergoing cervical spine surgery. Level of Evidence: 3
Effect of triple therapy in patients with asthma-COPD overlap . Int J Clin Pharmacol Ther. 2019 Jun 24;: Authors: Ishiura Y, Fujimura M, Ohkura N, Hara J, Kasahara K, Ishii N, Tamaki T, Shimizu T, Nomura S Abstract OBJECTIVE: Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is of increasing interest because ACO patients have significantly worse outcomes, leading to greater social and economic burdens compared with asthma or COPD alone. Some guidelines for ACO recommend triple therapy with inhaled corticosteroids, long-acting β2 agonists, and long-acting muscarinic antagonists. H...
We’re all gonna die. It’s a simple truth that an astounding number of people neglect to acknowledge or accept. Some people die sudden, unexpected deaths, but most eventually fall victim to chronic or terminal conditions like COPD, heart failure or cancer. As a palliative care physician, I often meet patients who have had conversations with […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more.
Pursed lip breathing is a breathing technique that can help people get more air into their lungs. This technique may be particularly beneficial for people with respiratory conditions, such as COPD. Learn more about the benefits of pursed lip breathing and how to do it here.
Condition: Pulmonary Disease, Chronic Obstructive Intervention: Behavioral: Pulmonary Telerehabilitation Sponsor: VA Office of Research and Development Not yet recruiting
Approximately 16 million Americans have COPD.