Monitoring structural features, biocompatibility and biological efficacy of gamma-irradiated methotrexate-loaded spray-dried microparticles.

This study demonstrated the feasibility of the gamma irradiated spray dried PLGA microparticles for prolonged release of MTX, supporting a promising antitumor-drug delivery system for parenteral (subcutaneous) or pulmonary use. PMID: 28866185 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/28866185?dopt=Abstract

Source: Appl Human Sci - September 4, 2017 Category: Physiology Authors: de Oliveira AR, Mesquita PC, Machado PRL, Farias KJS, de Almeida YMB, Fernandes-Pedrosa MF, Cornélio AM, do Egito EST, da Silva-Júnior AA Tags: Mater Sci Eng C Mater Biol Appl Source Type: research