Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease

Conclusions
Our results reveal the UPS, and CYLD specifically, as an important contributor to IBD pathogenesis, which is favoured by both genetic and microbial factors.

Source: Gut - July 8, 2014 Category: Gastroenterology Authors: Cleynen, I., Vazeille, E., Artieda, M., Verspaget, H. W., Szczypiorska, M., Bringer, M.-A., Lakatos, P. L., Seibold, F., Parnell, K., Weersma, R. K., Mahachie John, J. M., Morgan-Walsh, R., Staelens, D., Arijs, I., De Hertogh, G., Muller, S., Tordai, A., Tags: Crohn's disease Inflammatory bowel disease Source Type: research