Survival Impact of Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome Positive (Ph+) de novo Acute Myeloid Leukemia (AML)

Ph+ de novo AML is a rare and lethal entity conventionally requiring allogeneic stem cell transplantation as the only curative measure. TKIs have been shown to be effective in Ph+ AML. However, the impact on survival and durability of response in this high-risk population remains unclear.

Source: Clinical Lymphoma, Myeloma and Leukemia - September 1, 2017 Category: Hematology Authors: Onyee Chan, Seongseok Yun, Anna Halpern, Hani Babiker, Srinath Sundararajan, Jorge Ramos, Paul Hendrie, Utkarsh Acharya Source Type: research