Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis

In conclusion, O-GlcNAc modification is essential for cold-induced thermogenesis and mitochondrial biogenesis in BAT. Glucose flux into BAT may be a signal to maintain BAT physiological responses.

Source: Diabetes - August 22, 2017 Category: Endocrinology Authors: Ohashi, N.; Morino, K.; Ida, S.; Sekine, O.; Lemecha, M.; Kume, S.; Park, S.-Y.; Choi, C. S.; Ugi, S.; Maegawa, H. Tags: Insulin Action-Cellular and Molecular Metabolism Source Type: research