Evaluation of Antihyperglycemic Property from Syzygium oleana (Magnoliopsida: Myrtaceae) Pericarp

This study was to find out scientific evidence that the methanolic extract of Syzygium oleana pericarp has an antihyperglycemic property to manage type 2 diabetes. Materials and Methods: The secondary-metabolites' profile of methanolic extract of S. oleana pericarp was screened by phytochemical analysis methods, its antioxidant property was judged with DPPH scheme and linked to the ascorbic acid at the wavelength of 517 nm and its IC50 value was determined based on the Log dose inhibition curve. The paired samples t-test was used to determine the difference of blood glucose level of Rattus norvegicus before and after treatment by utilizing SPSS software version 24. The treated extract at 100 and 200 mg kg–1 b.wt., administered to the glucose-induced diabetic rat and compared to the metformin (65 mg kg–1 b.wt.). Histopathological investigations performed the evidence that the extract could improve pancreatic β-cells by depresses necrosis of pancreatic β-cells in the islet cells based on one way ANOVA (p
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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This article published in 2015 discusses some of the negative issues that have been associated with sitting including: Impeded cardiovascular and metabolic function Depression and psychological distress (for example, a “mental funk”) Spike in blood sugar levels Increased risk for heart attack, type 2 diabetes, insomnia, arthritis, certain types of cancers, and premature death As you can see, this list is comprised of serious issues, and the author of the article gives some great suggestions for reducing your time sitting as well as for combating sitting’s negative effects. It is interesting to note tha...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Health-related Source Type: blogs
This study aimed to ascertain antidiabetic potential of methanolic extract of Pseuduvaria macrophylla bark (PM) using streptozotocin-nicotinamide induced diabetic rat models. Various phytochemical and biochemical properties of the plant have been evaluated. The results showed that the extract has potentially normalized the elevated blood glucose levels by upregulating the insulin and C-peptide levels and alleviated oxidative stress by improving glutathione (GSH) and reducing lipid peroxidation (LPO) in the diabetic rats. In addition, PM has drastically downregulated the levels of pro-inflammatory cytokines and transforming...
Source: Journal of Applied Biomedicine - Category: Biotechnology Source Type: research
DIABETES type 2 symptoms include unexplained weight loss, tiredness and frequently needing the toilet. If you develop the condition it is important to take steps to control your blood sugar levels, as failing to do so can cause further life threatening problems. These are seven problems you can develop due to the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES type 2 is more likely to appear as we get older, while diabetes type 1 usually appears shortly after birth. Diabetes symptoms include frequently needing the loo, feeling more hungry and thirsty than usual and unexplained weight loss. If you suffer from the condition, you should eat this much fruit and veg a day in your diet to help maintain your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 47-year-old man is evaluated during a follow-up examination. He is obese and has hypertension, type 2 diabetes mellitus, and obstructive sleep apnea. He reports that he has always has been overweight, and over the years, his weight has gradually increased to 123 kg (271 lb). During the past 2 years, he has tried several commercial diets; a dietician-monitored, calorie-restricted diet; increased physical activity; orlistat; and a combination of these interventions, all without achieving sustained weight...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Primary Care Source Type: blogs
A surprising (but welcome) side effect of a therapy for obsessive-compulsive disorder may pave the way for a new approach to treating type 2 diabetes — and offer new insights into the links between obesity and the metabolic disease that afflicts close to 1 in 10 American adults.The therapy in...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news
DIABETES type 2 is more likely to appear as we get older, while diabetes type 1 usually appears shortly after birth. Diabetes symptoms include frequently needing the loo, feeling more hungry and thirsty than usual and unexplained weight loss. If you suffer from the condition, you should eat this much fruit and veg a day in your diet to help maintain your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
DIABETES type 2 is more likely to appear as we get older, while diabetes type 1 usually appears shortly after birth. Diabetes symptoms include frequently needing the loo, feeling more hungry and thirsty than usual and unexplained weight loss. If you suffer from the condition, you should eat this much fruit and veg a day in your diet to help maintain your blood sugar levels.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Date: Wednesday, 06 06, 2018; Speaker: Anne Sumner, MD, Senior Investigator, , Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, NIDDK; Stephanie Chung, MBBS, Assistant Clinical Investigator, , Section on Ethnicity and Health, Diabetes, Endocrinology , and Obesity Branch, NIDDK; Building: Building 10 (Clinical Center); Lipsett Amphitheater; CME Credit; Videocast Event
Source: NIH Calendar of Events - Category: American Health Source Type: events
Publication date: Available online 27 April 2018 Source:Nutrition, Metabolism and Cardiovascular Diseases Author(s): O. Vaccaro, M. Masulli, G. Riccardi TOSCA.IT is an institutional, non-industry-supported, head-to-head study comparing long term cardiovascular effects, efficacy and safety of two antidiabetes drugs (pioglitazone vs sulphonylureas) used in combination with metformin in patients with type 2 diabetes mellitus. The study results show that in the absence of clinically evident cardiovascular disease both treatment strategies represent suitable alternatives; however, in consideration of the greater durability of ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
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