Performance evaluation of a high-resolution brain PET scanner using four-layer MPPC DOI detectors.

Performance evaluation of a high-resolution brain PET scanner using four-layer MPPC DOI detectors.
Phys Med Biol. 2017 Jul 28;:
Authors: Watanabe M, Saito A, Isobe T, Ote K, Yamada R, Moriya T, Omura T
Abstract
A high-resolution positron emission tomography (PET) scanner dedicated to brain studies was developed, and its performance was evaluated. A four-layer depth of interaction (DOI) detector was designed; it contains five detector units axially lined up per layer board. Each of the detector units consists of a LYSO scintillator array finely segmented (1.2 mm) and an 8 × 8 array of multi-pixel photon counters (MPPCs). The new scanner was designed to form a detector ring of 430-mm diameter with 32 detector modules and 168 detector rings with a 1.2-mm pitch. The transaxial and axial field of views (FOVs) are 330 mm in diameter and 201.6 mm, respectively, which are sufficient to measure a whole human brain. The single-event data generated at each detector module were transferred to the data acquisition servers through optical fiber cables. The single-event data from all detector modules were merged and processed to create coincidence event data in on-the-fly software in the data acquisition servers. The performance of the brain PET scanner was evaluated. The system spatial resolutions were less than 1.3 mm FWHM throughout the whole FOV. The system sensitivity was 21.4 cps/kBq as measured using an 18F line source aligned with the cent...

Source: Physica Medica - July 28, 2017 Category: Physics Authors: Watanabe M, Saito A, Isobe T, Ote K, Yamada R, Moriya T, Omura T Tags: Phys Med Biol Source Type: research