Acid-gastric antisecretory effect of the ethanolic extract from Arctium lappa L. root: role of H + , K + -ATPase, Ca 2+ influx and the cholinergic pathway

ConclusionOur results reinforce the gastric antisecretory properties of preparations obtained fromArctium lappa, and indicate that the mechanisms involved in EET antisecretory effects include a moderate reduction of the H+, K+-ATPase activity associated with inhibitory effects on calcium influx and of cholinergic pathways in the stomach muscle.

http://link.springer.com/10.1007/s10787-017-0378-4

Source: Inflammopharmacology - July 28, 2017 Category: Drugs & Pharmacology Source Type: research