Differences in characteristics and outcomes between community- and hospital-acquired acute kidney injury: A systematic review and meta-analysis 
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Differences in characteristics and outcomes between community- and hospital-acquired acute kidney injury: A systematic review and meta-analysis
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Clin Nephrol. 2017 Jul 24;:
Authors: Inokuchi R, Hara Y, Yasuda H, Itami N, Terada Y, Doi K
Abstract
INTRODUCTION: No comprehensive review has examined the difference between community-acquired (CA) and hospital-acquired (HA) acute kidney injury (AKI) in terms of patient characteristics, in-hospital mortality, and hospital stay length.
MATERIALS AND METHODS: We conducted a systematic review and meta-analysis of observational studies, using MEDLINE, EMBASE, Web of Science, Google Scholar, and the Cochrane Library from their inceptions to April 10, 2016. Observational studies that (1) were published in peer-reviewed journals; (2) compared CA-AKI with HA-AKI, irrespective of the AKI definition during the same period; and (3) investigated in-hospital mortality and length of hospital stay were studied. Differences in the patients' baseline characteristics were analyzed, and a meta-analysis was conducted to compare the in-hospital mortality and length of hospital stay.
RESULTS: Eight eligible observational studies with 17,939 patients were included. The systematic review showed that patients with CA-AKI had a significantly higher rate of AKI stage 3 compared with those with HA-AKI. The meta-analysis revealed that patients with CA-AKI showed significantly lower in-hospital mortal...

Source: Clinical Nephrology - July 24, 2017 Category: Urology & Nephrology Authors: Inokuchi R, Hara Y, Yasuda H, Itami N, Terada Y, Doi K Tags: Clin Nephrol Source Type: research