Disconnection as a mechanism for social cognition impairment in multiple sclerosis

Conclusions:
These results indicate that a diffuse pattern of NAWM damage in MS contributes to social cognition impairment in the ToM domain, probably due to a mechanism of disconnection within the social brain network. Gray matter pathology is also expected to have an important role; thus further research is required to clarify the neural basis of social cognition impairment in MS.

Source: Neurology - July 3, 2017 Category: Neurology Authors: Batista, S., Alves, C., dAlmeida, O. C., Afonso, A., Felix-Morais, R., Pereira, J., Macario, C., Sousa, L., Castelo-Branco, M., Santana, I., Cunha, L. Tags: MRI, All Neuropsychology/Behavior, Neuropsychological assessment, Multiple sclerosis ARTICLE Source Type: research