Oestrogen induced downregulation of TFPI expression is mediated by ERα

Conclusion: Our data establish a direct and time dependent regulation of TFPI expression by oestrogens through the ERα at the transcriptional level.

Source: Thrombosis Research - April 30, 2014 Category: Hematology Authors: Huda Omar Ali, Benedicte Stavik, Elisabeth Dørum, Nina Iversen, Per Morten Sandset, Grethe Skretting Tags: Coagulation and Fibrinolysis Source Type: research