Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

Facioscapulohumeral muscular dystrophy (FSHD) is most commonly inherited in an autosomal dominant pattern and caused by the abnormal expression of DUX4 in skeletal muscle. The DUX4 transcription factor has DNA...

Source: Skeletal Muscle - June 21, 2017 Category: Research Authors: Premi Haynes, Kelly Kernan, Suk-Lin Zhou and Daniel G. Miller Source Type: research