Pyramidal tract activation due to subthalamic deep brain stimulation in Parkinson's disease

ConclusionsDirect pyramidal tract activation can occur at stimulation thresholds that are within the range used in clinical routine. This spread of current compromises increase in stimulation strengths and is related to the development of side effects such as speech disturbances with chronic stimulation. © 2017 International Parkinson and Movement Disorder Society

Source: Movement Disorders - June 7, 2017 Category: Neurology Authors: Philipp Mahlknecht, Harith Akram, Dejan Georgiev, Elina Tripoliti, Joseph Candelario, Andre Zacharia, Ludvic Zrinzo, Jonathan Hyam, Marwan Hariz, Thomas Foltynie, John C. Rothwell, Patricia Limousin Tags: Research Article Source Type: research