Multiple signals at the extended 8p23 locus are associated with susceptibility to systemic lupus erythematosus

Conclusions
Our results implicate multiple (known+novel) SLE signals/genes at the extended 8p23 locus, beyond previously reported signals/genes, and suggest that this broad locus contributes to SLE risk through the effects of multiple genes/pathways.

Source: Journal of Medical Genetics - May 26, 2017 Category: Genetics & Stem Cells Authors: Demirci, F. Y., Wang, X., Morris, D. L., Feingold, E., Bernatsky, S., Pineau, C., Clarke, A., Ramsey-Goldman, R., Manzi, S., Vyse, T. J., Ilyas Kamboh, M. Tags: Complex traits Source Type: research