Do anti-malarials in Africa meet quality standards? The market penetration of non quality-assured artemisinin combination therapy in eight African countries

Quality of artemisinin-based combination therapy (ACT) is important for ensuring malaria parasite clearance and protecting the efficacy of artemisinin-based therapies. The extent to which non quality-assured A...
Source: Malaria Journal - Category: Infectious Diseases Authors: Source Type: research

Related Links:

Date: Wednesday, 11 13, 2019; Speaker: Laura Amo, Ph.D. , Postdoctoral Fellow, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases; Building: Building 45 (Natcher Building); Ruth Kirschstein Auditorium
Source: NIH Calendar of Events - Category: American Health Source Type: events
We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01099
Source: Journal of Medicinal Chemistry - Category: Chemistry Authors: Source Type: research
by Xue Li, Sudhir Kumar, Marina McDew-White, Meseret Haile, Ian H. Cheeseman, Scott Emrich, Katie Button-Simons, Fran çois Nosten, Stefan H. I. Kappe, Michael T. Ferdig, Tim J. C. Anderson, Ashley M. Vaughan Determining the genetic basis of fitness is central to understanding evolution and transmission of microbial pathogens. In human malaria parasites (Plasmodium falciparum), most experimental work on fitness has focused on asexual blood stage parasites, because this stage can be easily cultured, although the transmission of malaria requires both femaleAnopheles mosquitoes and vertebrate hosts. We explore a powerf...
Source: PLoS Genetics - Category: Genetics & Stem Cells Authors: Source Type: research
We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Funding Opportunity RFA-AI-19-059 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to stimulate basic research, discovery, and early translational research to enable and accelerate the generation of highly efficacious pre-erythrocytic stage, sporozoite-based vaccines. Cross-fertilization and collaboration among investigators from malaria vaccine research and other basic research areas such as parasite biology, parasite genomics, pathogenesis, and host immunology are highly encouraged. The goal is to generate one or more promising vaccine candidates against human malaria that exhibit performan...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Malaria is one of the deadliest infectious diseases caused by protozoan parasite of Plasmodium spp. Increasing resistance to anti-malarials has become global threat in control of the disease and demands for novel...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
More News: African Health | Infectious Diseases | Malaria | Parasitic Diseases | Parasitology