Pharmacokinetics of ingenol mebutate gel under maximum use conditions in large treatment areas.

CONCLUSION: Subnanomolar systemic exposure to ingenol mebutate was measured after application of the gel to approximately 250 cm(2) on the full face, scalp, or arm under maximum use conditions. No clinically relevant systemic adverse reactions were observed, and local skin responses were manageable. PMID: 28524709 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research