Comparing the Vitex-castus extract and cabergoline effects on estrous induction in female dogs

AbstractCabergoline is used to induce estrus, stop lactation, and induce abortion in small animals. The specific doses of Vitagnus extract have almost identical properties of cabergoline that reduce prolactin and increase the concentration of FSH hormone. The aim of this study was to compare the effect ofVitex agnus-castus extract and cabergoline on prolactin concentration and hormonal changes associated with the onset of estrous cycle in dogs. Twelve healthy adult cyclic female-mix breed dogs were selected and randomly aligned in treatment (6 dogs, Vitagnus extract 1.5  ml daily for 5 weeks, 80–90 mg/ml, PO) and control groups (6 dogs, cabergoline, daily for 5 weeks, 5 μg/kg, PO). Blood sampling and vaginal smears were taken weekly. Serum samples were stored at −20 °C until prolactin, estradiol, and progesterone were measured by ELISA method. Based on vaginal cytology results, four (cabergoline) and three (Vitagnus) dogs were in the estrous phase after 5 weeks of treatment. The average concentration of the prolactin was not changed during 5 weeks and between two groups. There was no significant difference in progesterone and estradiol levels be tween groups. The changes of estradiol concentration were significant during the 5 weeks (p 
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

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Publication date: Available online 18 November 2019Source: The Journal of Molecular DiagnosticsAuthor(s): Elisabetta Macerola, Anello Marcello Poma, Agnese Proietti, Rossana Romani, Liborio Torregrossa, Clara Ugolini, Teresa Rago, Paolo Vitti, Fulvio BasoloPatients with indeterminate thyroid nodules (Bethesda III and IV) are often treated with diagnostic lobectomy, which in the majority of cases represent an overtreatment. A reliable rule-out molecular test could spare patients unnecessary surgery. Stained smears of 88 indeterminate thyroid nodules with histological diagnosis of follicular-patterned tumors were selected: 3...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Conclusion: A large number of the participating laboratories (77%) had an overall score of >80% for all exercises, demonstrating acceptable baseline performance of EQAS registered laboratories. However, continued EQAS participation could further improve the quality of results.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Patients with indeterminate thyroid nodules (Bethesda III and IV) are often treated with diagnostic lobectomy, which in the majority of cases represent an overtreatment. A reliable rule-out molecular test could spare patients unnecessary surgery. Stained smears of 88 indeterminate thyroid nodules with histological diagnosis of follicular-patterned tumors were selected: 34 follicular adenomas (FA), 34 follicular variant papillary thyroid carcinomas (FVPTC), and 20 noninvasive follicular neoplasms with papillary-like nuclear features (NIFTP).
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Source Type: research
A good deal of clinical diagnostics are effectively performed by cytologists who examine cells through a microscope for signs of disease. This is an imperfect, slow process that depends on the training, focus, and attention to detail of the cytologis...
Source: Medgadget - Category: Medical Devices Authors: Tags: Diagnostics Informatics Medicine Oncology Pathology Source Type: blogs
CONCLUSION: Changing the sexual image of the vaccine could help to establish a collective vaccination policy. Public health policies play an essential role by working with general practitioners and by increasing visibility on the web. The usefulness of the vaccine in 2019 seems to be questioned by Internet users as shown by their major approval of cervical smears. However, these two methods remain complementary in the fight against cervical cancer. PMID: 31718831 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research
The studies comparing the diagnostic efficacy of liquid-based cytology (LBC) and smear cytology (SC) of pancreatic tissue sampling obtained via endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) are still insufficient. Results were controversial. We compared the diagnostic efficiency of LBC and SC of EUS-FNA of pancreatic lesions in one of the largest tertiary hospitals in China.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Source Type: research
Conclusion: EP provides monolayered cervical smears with vivid morphological details, leading to reduced screening time and relatively higher pick-up of infections and low-grade cervical lesions as compared to conventional smears. The availability of such low-cost devices may enable wider application of cytology-based cervical cancer screening in low-resource countries.
Source: CytoJournal - Category: Pathology Authors: Source Type: research
This study is registered with ClinicalTrials.gov, NCT02193776, and all patients have completed follow-up.FindingsBetween Oct 24, 2014, and Dec 15, 2015, we enrolled 180 patients with drug-susceptible tuberculosis (59 were randomly assigned to BloadPaZ, 60 to B200PaZ, and 61 to HRZE) and 60 patients with rifampicin-resistant tuberculosis. 57 patients in the BloadPaZ group, 56 in the B200PaZ group, and 59 in the HRZE group were included in the primary analysis. B200PaZ produced the highest daily percentage change in TTP (5·17% [95% Bayesian credibility interval 4·61–5·77]), followed by BloadPaZ (4&...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
(Natural News) In response to having his science-based content arbitrarily de-platformed from Google’s search results back in June, Dr. Joseph Mercola of the popular Mercola.com health website is boldly sounding the alarm about Google’s quiet entry into the pharmaceutical business, and how this is negatively affecting the overall functionality and integrity of Google’s search engine....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
In conclusion, while travelling to endemic countries, people should be informed about the importance of malaria prophylaxis and prophylaxis should be commenced immediately and continued appropriately. Additionally, malaria should always be considered in the differential diagnosis of high fever for the patients who admitted to the hospital with a travelling history to these countries. PMID: 31709945 [PubMed - in process]
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
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