Assessment of clinically relevant bleeding as a surrogate outcome for major bleeding: validation by meta ‐analysis of randomized controlled trials

ConclusionDespite an apparent correlation between CRB and major bleeding in major orthopedic surgery, AF and for double‐blind acute VTE studies, the wide CIs suggest that CRB might not be an acceptable surrogate outcome in any of these settings.This article is protected by copyright. All rights reserved.

Source: Journal of Thrombosis and Haemostasis - May 1, 2017 Category: Hematology Authors: S. Laporte, C. Chapelle, L. Bertoletti, E. Ollier, P. Zufferey, J ‐C Lega, A. Merah, H. Décousus, S. Schulman, G. Meyer, M. Cucherat, P. Mismetti Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research