Novel Signs and Their Clinical Utility in Diagnosing Complex Regional Pain Syndrome (CRPS): A Prospective Observational Cohort Study

The objectives of our study were to define and validate 4 bedside tests, to identify the prevalence of positive tests in patients with CRPS and other chronic pain conditions, and to assess the clinical utility (sensitivity, specificity, positive predictive value, negative predictive value) for identifying CRPS within a Fracture cohort. This was a single UK teaching hospital prospective cohort study with 313 recruits from pain-free volunteers and patients with chronic pain conditions. Four novel tests were Finger Perception (FP), Hand Laterality identification (HL), Astereognosis (AS), and Body Scheme (BS) report. Five questionnaires (Brief Pain Inventory, Upper Extremity Functional Index, Lower Extremity Functional Index, Neglect-like Symptom Questionnaire, Hospital Anxiety and Depression Score) assessed the multidimensional pain experience. Results: FP and BS were the best performing tests. Prospective monitoring of fracture patients showed that out of 7 fracture patients (total n=47) who had both finger misperception and abnormal BS report at initial testing, 3 developed persistent pain with 1 having a formal diagnosis of CRPS. Discussion: Novel signs are reliable, easy to perform, and present in chronic pain patients. FP and BS have significant clinical utility in predicting persistent pain in a fracture group thereby allowing targeted early intervention.
Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Original Articles Source Type: research

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ABSTRACT Objectiv:e to analyze the relationship of anxiety and depression in the preoperative period with the presence of pain in the postoperative period. Method: cohort study conducted at a university hospital in the state of Minas Gerais (Brazil), between february and July 2017, with 65 patients. A collection instrument was elaborated for the demographic and clinical characteristics. The Hospital Anxiety and Depression Scale was used to assess anxiety and depression; pain intensity was measured using the Verbal Numerical Scale. Data were submitted to descriptive and inferential statistical analysis. Results: according t...
Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
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Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
Hui Xu1,2,3, Chenguang Guo1, Haining Li1, Lin Gao2, Ming Zhang1* and Yuan Wang1* 1Department of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China 2Key Laboratory of Biomedical Information Engineering of Education Ministry, Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an, China 3Faculty of Dentistry, University of Toronto, Toronto, ON, Canada Background and Purpose: Hemifacial spasm (HFS) is a rare neuromuscular disorder characterized by unilateral, involuntary, and paroxysmal contractions of orofacial muscles. To eluci...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Report Current Issue amputation pain phantom limb pain rehabilitation therapy virtual reality Source Type: research
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Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
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Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Clinical Research Source Type: research
Abstract BackgroundComplex regional pain syndrome (CRPS) is difficult to effectively treat with unimodal approaches. ObjectiveTo investigate whether CRPS can be effectively treated in a comprehensive interdisciplinary pain management program. DesignObservational cohort study of 49 patients aged 18–89 who fulfilled ‘Budapest Criteria’ for CRPS and completed an interdisciplinary pain management program. Preprogram to postprogram changes in physical functioning, perceived disability, emotional functioning, acceptance, coping, and pain were assessed. The measures used included: Pain Disability Index, Six minu...
Source: Pain Medicine - Category: Anesthesiology Authors: Tags: Original Source Type: research
Abstract BackgroundComplex regional pain syndrome (CRPS) is difficult to effectively treat with unimodal approaches. ObjectiveTo investigate whether CRPS can be effectively treated in a comprehensive interdisciplinary pain management program. DesignObservational cohort study of 49 patients aged 18–89 who fulfilled ‘Budapest Criteria’ for CRPS and completed an interdisciplinary pain management program. Preprogram to postprogram changes in physical functioning, perceived disability, emotional functioning, acceptance, coping, and pain were assessed. The measures used included: Pain Disability Index, Six minu...
Source: Pain Medicine - Category: Anesthesiology Authors: Tags: NEUROPATHIC PAIN SECTION Source Type: research
Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by extremely severe pain, swelling, and changes in the skin, and causes psychological sequelae such as depression, anxiety, and deteriorated quality of life. CRPS patients’ risk for suicide has been reported to be considerably higher than that not only of general populations but also of other chronic pain populations. Considering that conceiving, planning, and committing suicide is closely related to the decline of executive function that regulates cognitive flexibility, planning and organizing, and response inhibition ability, this preli...
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research
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