The incidence of long heterochromatic polymorphism variants in infants conceived through assisted reproductive technologies

This study included a total of 647 infants, including 189 conceived by ICSI, 177 by IVF, and 281 naturally conceived (NC). Variants were observed in 13.23% of ICSI, 15.82% of IVF and 12.46% of NC infants, showing that the incidence of variants does not appear to be significantly different between infants conceived using assisted reproductive technologies and infants conceived naturally. Because the parents of these infants were not karyotyped, we can only speculate as to whether these variants were directly inherited. This study concludes that infants born from infertile parents using assisted reproductive technologies to achieve pregnancy do not appear to be any more likely than NC infants of fertile parents to possess long heterochromatic variants.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research