Ovarian tissue transplantation for hormone replacement
Publication date: Available online 16 August 2018Source: Reproductive BioMedicine OnlineAuthor(s): RA Anderson (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 18, 2018 Category: Reproduction Medicine Source Type: research

New strategies of ovarian stimulation based on the concept of ovarian follicular waves: from conventional to random and double stimulation
Publication date: Available online 11 August 2018Source: Reproductive BioMedicine OnlineAuthor(s): Giovanna Sighinolfi, Sesh Kamal Sunkara, Antonio La MarcaAbstractThe theory of a multicyclic development of follicles during the menstrual cycle prompted new approaches to ovarian stimulation, such as starting gonadotrophins for ovarian stimulation at any time during the menstrual cycle or using double stimulation during it, with stimulation in both the follicular and luteal phases. Because of the asynchrony between endometrial receptivity and embryo development with a ‘non-conventional start’ stimulation, all the...
Source: Reproductive BioMedicine Online - August 11, 2018 Category: Reproduction Medicine Source Type: research

Response: how PGS/PGT-A laboratories succeeded in losing all credibility
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): Francesca Romana Grati, Gloria Gallazzi, Lara Branca, Federico Maggi, Giuseppe Simoni, Yuval Yaron (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

Editorial Board
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

Contents
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

Is 45 years-of-age the cut-off for using autologous oocytes?
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): John L. Yovich, Michael J. Chapman, Kevin N. Keane, Julian Savulescu (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

A big step forward for PGT-M?
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): Sharyn Stock-Myer, Martin Johnson (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

The emperor still looks naked
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): Peter BraudeAbstractPreimplantation genetic screening for aneuploidy continues to excite disagreement, discussion and confusion in the field of reproductive medicine. This commentary provides a contribution to the ongoing debate. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

How PGS/PGT-A laboratories succeeded in losing all credibility
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): Norbert Gleicher, Vitaly A. Kushnir, David H. Barad (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

Response: how PGS/PGT-a laboratories succeeded in losing all credibility
Publication date: August 2018Source: Reproductive BioMedicine Online, Volume 37, Issue 2Author(s): Santiago Munné, Sarah Yarnal, Pedro A. Martinez-Ortiz, Mark Hughes, Tony Gordon (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - August 1, 2018 Category: Reproduction Medicine Source Type: research

GnRH antagonist for endometrial priming in an oocyte donation programme: a prospective, randomized controlled trial
ConclusionsFor women with ovulatory cycles undergoing oocyte donation, the outcomes are similar between GnRH antagonist and down-regulated hormone replacement protocols. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 31, 2018 Category: Reproduction Medicine Source Type: research

The UK's anomalous 10-year limit on oocyte storage: time to change the law
Publication date: Available online 29 July 2018Source: Reproductive BioMedicine OnlineAuthor(s): Peter Bowen-Simpkins, Jinjun J Wang, Kamal K AhujaAbstractThere has been a growing recognition in the UK that the statutory storage limit for frozen eggs, which currently stands at 10 years, requires a review. The UK regulator, the Human Fertilization and Embryology Authority (HFEA), has recognized the problem and the Equality and Human Rights Commission is also sympathetic with the demand to change the current legislation. There is also strong desire on the part of assisted reproductive technology (ART) professionals and patie...
Source: Reproductive BioMedicine Online - July 29, 2018 Category: Reproduction Medicine Source Type: research

In-depth quantitative proteome analysis of seminal plasma from men with oligoasthenozoospermia and normozoospermia
ConclusionsOur seminal plasma proteome research provides new complementary high-confidence data, and also enhances understanding of the pathogenic mechanisms in oligoasthenozoospermia. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 19, 2018 Category: Reproduction Medicine Source Type: research

WITHDRAWN: Is 45 years-of-age the cut-off for using autologous oocytes?
Publication date: Available online 19 June 2018Source: Reproductive BioMedicine OnlineAuthor(s): John L Yovich, Michael J Chapman, Kevin N Keane, Julian SavulescuThe Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.rbmo.2018.06.001. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 18, 2018 Category: Reproduction Medicine Source Type: research

Preimplantation genetic testing for complex chromosomal rearrangement carriers by next-generation sequencing
ConclusionThese results strongly support the use of NGS for CCR carriers. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 18, 2018 Category: Reproduction Medicine Source Type: research

Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management – meta-analyses
Publication date: Available online 10 July 2018Source: Reproductive BioMedicine OnlineAuthor(s): Daniele Santi, Giorgia Spaggiari, Manuela SimoniAbstractConventional semen analyses have limitations in male infertility diagnosis and prognosis. Assessment of sperm DNA fragmentation (sDF) has been proposed to discriminate fertile from infertile men and predict FSH treatment response in infertile men, although a comprehensive evaluation of this is not available. The aims of these meta-analyses were to assess the power of sDF in male infertility diagnosis and its role in predicting FSH therapy response in infertile men. Two lit...
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Low anti-Müllerian hormone concentration is associated with increased risk of embryonic aneuploidy in women of advanced age
Publication date: Available online 13 April 2018Source: Reproductive BioMedicine OnlineAuthor(s): Xiao Jiang, Junhao Yan, Yan Sheng, Mei Sun, Linlin Cui, Zi-Jiang ChenAbstractResearch questionDoes an association exist between serum anti-Müllerian hormone (AMH) level, the marker of biological ovarian age, and embryonic aneuploidy risk in recurrent spontaneous miscarriage (RSM) patients of reproductive age?DesignThis retrospective study included a total of 422 IVF cycles of 394 unexplained RSM patients undergoing preimplantation genetic testing for aneuploidy (PGT-A), enrolled from January 2014 to December 2016. Subject...
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Ulipristal acetate for the management of large uterine fibroids associated with heavy bleeding: a review
Publication date: Available online 21 April 2018Source: Reproductive BioMedicine OnlineAuthor(s): Jacques Donnez, Guillaume E. Courtoy, Olivier Donnez, Marie-Madeleine DolmansAbstractUlipristal acetate (UPA), a selective progesterone receptor modulator (SPRM), offers new therapeutic options for the clinical management of large uterine fibroids associated with heavy menstrual bleeding or with other moderate or severe symptoms (bulk symptoms, pelvic pain, decreased quality of life). SPRM are synthetic compounds that exert an agonist or antagonist effect on target tissues by their binding to progesterone receptors. UPA reduce...
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Distinct changes in the proteome profile of endometrial tissues in polycystic ovary syndrome compared with healthy fertile women
ConclusionsThe processes related to the differentially expressed proteins play important roles in fecundity and fecundability. The present study may reveal the cause of various endometrial aberrations as a limiting factor for achieving pregnancy in PCOS women. (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-021 - Angle between first and second polar bodies is significantly associated with clinical outcome
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Mercedes Regueira, Alison Campbell, Ioannis Gallos, Sue Montgomery, Lucy Jenner, Audrey Wachter, Stacey Wheat, Fiona Foad, Rachel Smith, Lynne Nice, Ellen Armstrong, Simon Fishel (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-022 - Slow passive freezing for ovarian tissue shows comparable in vitro activation of primordial follicles with no difference in apoptosis compared to traditional controlled slow freezing
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Sylvie Lierman, Kelly Tilleman, Ria Cornelissen, Petra De Sutter (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-023 - Increasing efficiency of sperm cryobanking
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Hilde Cathrine Böhle Ockhammar, Kristina Miras Wardell, Julius Hreinsson (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-024 - Relationship between IMC size and blastocyst diameter with euplody
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Yolanda Cabello, Daniel Ordonez, Celia Romero, Aida Vaquero, Pedro De Castro, Nuria Lopez Velasco, Cristina Camara, Esther Lopez (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-025 - Advanced blastocyst development stage at the time of vitrification, is associated with increased implantation, regardless of morphology
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Louise Best, Sue Montgomery, Lynne Nice, Rachel Smith, Sharon Cocoran, Alex Page, Kathryn Berrisford, Alison Campbell (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-026 - Apolipoprotein A1: potential biomarker of embryo development and blastocyst implantation after prolonged embryo culture in a micro-droplet culture system
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Irma Virant Klun, Ales Jerin, Milan Skitek, Martin Stimpfel, Eda Vrtacnik Bokal (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-027 - Morphokinetic analysis of embryos in conventional IVF and ICSI cycles according to the level of sperm DNA fragmentation
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Mi Kyung Chung, Seong Hee Jeong, So Hee Bark, Mi Jin Ryu, Ju Hyun Park, Su Hyeon Kim, Hyeon Jeong Jeong, Myung Hee Kim, Hee Sun Lee (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-028 - The effect of high humidity culture conditions over embryo development: a continuous embryo monitoring assessment
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Carmela Albert, Naiara Gonzalez, Julian Marcos, Lucia Alegre, Belén Aparicio Ruiz, Jose María De Los Santos, Marcos Meseguer (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-029 - A mice model of fertility preservation for pre-pubertal girls: significant primordial follicle survival by cryopreservation, despite increased DNA break and decreased proliferation in granulosa cells both after chemotherapy and ovarian vitrification
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Ciler Celik Ozenci, Soner Celik, Sinan Ozkavukcu, Alp Can (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-030 - Oxidative status of the embryo's spent culture media as a new noninvasive tool for embryo selection
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Virginia Garcia Laez, Lucia Alegre, Raquel Del Gallego, Tzali Cnaani, Sergei Shnizer, Marcos Meseguer (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-031 - Are different developmental embryo potential and clinical outcome depending on the type of translocation?
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Diana Beltrán, Maria Jose De Los Santos, Laura Escrich, Arancha Delgado, Pilar Buendia, Amparo Mifsud, Alberto Tejera, Maria Fernanda Insua, Damià Castelló, Amparo Mercader (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-032 - Impact of twice blastocyst biopsies on clinical outcomes
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Duangsamon Leangkonkit, Pagawadee Ketcharoon, Rattanamon Koonthaweelab, Kitiya Janpanya, Kasorn Tiewsiri (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-033 - Comparision of two Ca2+ ionophores for assisted oocyte activation: morphocynetics and development
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Mercè Durban, Meritxell Martínez, Amelia Rodríguez, Josep Santaló, Rita Vassena (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-034 - Vitrification of mouse GV-oocytes by the means of nanoparticles
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Yasaman Abbasi, Farzaneh Baniasadi, Samira Hajiaghalou, Mohammad Reza Ghalamboran, Rouhollah Fathi (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-035 - Amino acids stimulate primordial follicle activation
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Parimah Alborzi, Rouhollah Fathi, Ramezan Khanbabaei, Mohammad Jafari Atrabi, Vahid Akbarinejad (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-036 - Embryo grading at the compaction stage is highly predictive of outcome
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Sue Montgomery, Ioannis Gallos, Rachel Smith, Lynne Nice, Lucy Jenner, Alex Page, Alison Campbell (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-037 - Embryo division kinetics is related to oocyte volume
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Viktor Nagorny (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Alpha author index 2018
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

2018 Alpha Biennial Congress – Welcome
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Contents
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

Fm
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-001 - Does vitamin D deficiency affect the IVF-ET outcomes in infertile Korean women?
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Jie Ohn Sohn, Ji Hyun Jun, Se Hee Kim, Min Ji Kim, Jeong Mook Lim, Hyun Jin Song (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-002 - Selection of the selected: a retrospective cohort comparison of blastocyst warming media and its influence on survival and live birth rates following vitrification, warming and single embryo transfer
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Hamish Barblett, Peter Roberts, Phill Matson, Simon Turner (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-003 - Does human embryo growth rate affect the outcome of vitrified-warmed blastocyst transfer?
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Yee Shen Chong, Melinda Ling Hou Chan, Heng Hao Tan (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-004 - Сhromosomal and morphological status of blastocysts from vitrified oocytes: a retrospective comparative study
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Petrova Ekaterina, Kornilov Nikolai, Pavlova Marina (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-005 - The type of relationship and age of the patient at the time of decision-making are factors associated with the future use of conditionally blocked donors
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Kelly Tilleman, Alexia Maldague, Petra De Sutter (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-006 - Measurement of the alpha-1 chain of haptoglobin in the media of in vitro fertilized human embryos
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Gergely Montsko, Krisztina Gödöny, Ákos Várnagy, József Bódis, Gábor László Kovács (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-007 - ICSI outcomes in couples with male factor infertility do not differ from a control group presenting tubal factor diagnoses
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Andrea Abdala, Laura Vargas, Ernesto Gómez Passanante, Sergio Provenzano, Javier Singla (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-008 - Comparison of artificial shrinkage efficiency on D5 and D6 blastocysts
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Ricardo Azambuja, Lilian Okada, Virginia Reig, Alice Tagliani Ribeiro, Leticia Proença, Shana Flach, Marta Hentschke, Mariangela Badalotti, Alvaro Petracco (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-009 - Decision making processes of women who seek social oocyte cryopreservation
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Ran Kim, Lyu Sang Woo, Yoon Tae Ki, Shim Sung Han, Jayeon Kim (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research

P-010 - Efficacy of preimplantation genetic screening in women with a history of spontaneous abortion(s) of eukaryotic or aneuploidy abortus
Publication date: May 2018Source: Reproductive BioMedicine Online, Volume 37, Supplement 1Author(s): Eun Jeong Yu, Sang Woo Lyu, Sung Han Shim, Tae Ki Yoon, Ja Yeon Kim (Source: Reproductive BioMedicine Online)
Source: Reproductive BioMedicine Online - July 11, 2018 Category: Reproduction Medicine Source Type: research