Capillary degeneration and right ventricular remodeling due to hypoxic stress with Sugen5416.

CONCLUSION: Capillary degeneration and activation of VEGF/ERK signaling pathway might be crucial to accelerate the cardiac remodeling due to hypoxic stress with Sugen5416.
PMID: 28460626 [PubMed - as supplied by publisher]

Source: Current Vascular Pharmacology - April 27, 2017 Category: Drugs & Pharmacology Authors: Woo E, Kato R, Imano H, Fujiwara Y, Ijiri Y, Okada Y, Yamaguchi T, Izumi Y, Yoshiyama M, Katsumata T, Hayashi T Tags: Curr Vasc Pharmacol Source Type: research