Nonvitamin K-dependent oral anticoagulants (NOACs) in chronic kidney disease patients with atrial fibrillation

Atrial fibrillation (AF) represents the most common arrhythmia in patients with chronic kidney disease (CKD). As in the general population, in CKD patients AF is associated with an increased risk of thromboembolism and stroke. However, CKD patients, especially those on renal replacement therapy (RRT), also exhibit an increased risk of bleeding, especially from the gastrointestinal tract.Oral anticoagulation is the most effective form of thromboprophylaxis in patients with AF presenting increased risk of stroke.

Source: Thrombosis Research - May 3, 2017 Category: Hematology Authors: L. Di Lullo, C. Ronco, M. Cozzolino, D. Russo, L. Russo, B. Di Iorio, A. De Pascalis, V. Barbera, M. Galliani, E. Vitaliano, C. Campana, F. Santoboni, A. Bellasi Tags: Review Article Source Type: research