Cancer: Identifying synergistic drug combinations
Nature Reviews Drug Discovery 16, 314 (2017).
doi:10.1038/nrd.2017.76
Author: Crunkhorn Sarah
Drug combinations are commonly used to counter drug resistance in cancer therapy. To identify synergistic drug target combinations, Han et al. have developed a scalable CRISPR-based double-knockout system that enables parallel pairwise gene knockout. Application of this system in a chronic myeloid leukaemia (CML)
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: CrunkhornSarah Tags: Research Highlight Source Type: research
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