Transcriptomic regulatory analysis of the dendritic cell response to post-lung transplant invasive aspergillosis

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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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ConclusionsIsolation of NTM or Aspergillus species from lung transplant recipients is uncommon. Adequate pre-transplant control and post-transplant management of NTM and Aspergillus infections allows for safe lung transplantation.
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
We present a case of primary Aspergillus appendicitis diagnosed by histologic examination in a patient who underwent lung transplantation.
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Source Type: research
We studied cytokine patterns predictive of subsequent invasive aspergillosis (IA) in lung transplant recipients (LTRs) with Aspergillus spp (Asp) colonization post-transplant.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
We report a case of successful treatment of probable invasive pulmonary aspergillosis due to A. lentulus and polymicrobial infection with Pseudomonas aeruginosa in a patient with relapsing granulomatosis with polyangiitis and recent high-dose steroid therapy.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research
This article is protected by copyright. All rights reserved.
Source: American Journal of Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imag...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Conclusion: PPFE seems to be a histologic finding that may partly overlap with other chronic lung diseases. There can be various underlying clinical states. This article is protected by copyright. All rights reserved.
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
Zaw Min, Manik Veer, Parth Rali, Anil Singh, Nitin BhanotLung India 2017 34(4):376-379Invasive aspergillosis generally occurs during the first 1–6 months after heart transplantation. It has been rarely seen in the first 2 weeks postcardiac transplant. We herein describe a unique case of invasive pulmonary aspergillosis (IPA) diagnosed on day 9 postorthotopic heart transplantation. The known risk factors for IPA in cardiac transplant recipients were not identified in our case. The organ recipients from the same donor did not report Aspergillus infection. Hospital environmental samplings failed to demonstrate Aspergill...
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
AbstractPurpose of ReviewTransplant patients are at high risk for invasive pulmonary aspergillosis, and the associated mortality is high. The purpose of this study is to review the pathogenesis of invasive pulmonary aspergillosis (IPA) in transplant patients.Recent FindingsThe pathogenesis of aspergillosis is multifactorial and results from a complex interplay between the pathogen and host. It is well recognized thatAspergillus causes IPA in immunocompromised patients. Recent studies have shown thatAspergillus might also cause diseases likely attributed to an unmodulated immune response in certain transplant recipients suc...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research
Publication date: Available online 18 May 2017 Source:Medical Mycology Case Reports Author(s): Enora Atchade, Sylvain Jean-Baptiste, Sandrine Houze, Claire Chabut, Laurent Massias, Yves Castier, Olivier Brugière, Hervé Mal, Philippe Montravers Aspergillus niger is usually considered to be a low virulence fungus, not commonly reported to cause invasive infections. Invasive pulmonary aspergillosis due to Aspergillus niger was diagnosed in a 43-year-old woman following bilateral lung transplantation. Intravenous voriconazole failed to control progression of the disease. Despite salvage therapy with a combinatio...
Source: Medical Mycology Case Reports - Category: Biology Source Type: research
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