Transcriptomic regulatory analysis of the dendritic cell response to post-lung transplant invasive aspergillosis

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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Conclusions. ISV is widely used in hematological pts with IFI also in diseases other than acute myeloid leukemia and it is overall well tolerated. ORR to ISV is at least comparable with other antifungal agents. A rec/ref underlying hematological disease impacts both on OS and response to ISV, while having an IFI refractory to other antifungal agents including azoles does not seem to compromise the response to ISV, although this promising result should be confirmed in prospective studies and larger groups of patients.DisclosuresBusca: Gilead: Honoraria, Membership on an entity's Board of Directors or advisory committees, Sp...
Source: Blood - Category: Hematology Authors: Tags: 203. Lymphocytes, Lymphocyte Activation, and Immunodeficiency, including HIV and Other Infections: Poster III Source Type: research
We report a case of Paragonimus westermani infection simultaneously affecting two separate organs that presented as both a pulmonary cavity and adrenal mass in an immunocompromised host.A 65-year-old male with a previous kidney transplant visited our clinic because of hemoptysis. Forty-three months earlier, bilateral spontaneous pneumothorax was diagnosed and treated with oxygen supplementation and right chest tube insertion. At that time, there was no demonstrable cavitary lesion in either lung and no mass in the adrenal glands (Fig. 1A, 1B). Computed tomography (CT) of the chest when the patient presented with hemoptysis...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
ConclusionsIsolation of NTM or Aspergillus species from lung transplant recipients is uncommon. Adequate pre-transplant control and post-transplant management of NTM and Aspergillus infections allows for safe lung transplantation.
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
We present a case of primary Aspergillus appendicitis diagnosed by histologic examination in a patient who underwent lung transplantation.
Source: Transplantation Proceedings - Category: Transplant Surgery Authors: Source Type: research
We studied cytokine patterns predictive of subsequent invasive aspergillosis (IA) in lung transplant recipients (LTRs) with Aspergillus spp (Asp) colonization post-transplant.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research
We report a case of successful treatment of probable invasive pulmonary aspergillosis due to A. lentulus and polymicrobial infection with Pseudomonas aeruginosa in a patient with relapsing granulomatosis with polyangiitis and recent high-dose steroid therapy.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Reports Source Type: research
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Source: American Journal of Transplantation - Category: Transplant Surgery Authors: Tags: Editorial Source Type: research
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imag...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
Conclusion: PPFE seems to be a histologic finding that may partly overlap with other chronic lung diseases. There can be various underlying clinical states. This article is protected by copyright. All rights reserved.
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
Zaw Min, Manik Veer, Parth Rali, Anil Singh, Nitin BhanotLung India 2017 34(4):376-379Invasive aspergillosis generally occurs during the first 1–6 months after heart transplantation. It has been rarely seen in the first 2 weeks postcardiac transplant. We herein describe a unique case of invasive pulmonary aspergillosis (IPA) diagnosed on day 9 postorthotopic heart transplantation. The known risk factors for IPA in cardiac transplant recipients were not identified in our case. The organ recipients from the same donor did not report Aspergillus infection. Hospital environmental samplings failed to demonstrate Aspergill...
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
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