Predicting long term cognitive outcomes after stroke using pre and post-stroke cognitive trajectories. (P2.098)

Conclusions:The rate of decline in cognition after stroke is predicted by rate of decline prior to stroke. Furthermore, greater change in rate of cognitive decline after incident stroke predicts dementia in individuals who were normal at the time of stroke. This may be a marker of both ongoing cerebrovascular injury and underlying neurodegenerative pathology.Disclosure: Dr. Thomas has nothing to disclose. Dr. Mattek has nothing to disclose. Dr. Wild has nothing to disclose. Dr. Dodge has nothing to disclose. Dr. Silbert has received research support from Eli-Lilly. Dr. Kaye has received personal compensation for activities with Lily LZAM and LZAN clinical trials. Dr. Erten-Lyons has received research support from Lundbeck, Eisai, Roche and Lilly.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Thomas, N., Mattek, N., Wild, K., Dodge, H., Silbert, L., Kaye, J., Erten-Lyons, D. Tags: Vascular Disease and Dementia Source Type: research