Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis (P1.349)

Conclusions:Rates of non-adherence varied by information source. Better parent-reported physical functioning was the strongest predictor of adherence. Parental involvement in adherence was associated with worse PedQL-school functioning and lower MS-Self-Efficacy measured confidence in controlling MS.Study Supported by: National MS Society (HC0148)Disclosure: Dr. Schwarz has nothing to disclose. Dr. Grover has nothing to disclose. Dr. Powell has nothing to disclose. Dr. Noguera has nothing to disclose. Dr. Mah has received research support from Biogen, Sanofi-Genzyme, and Novartis. Dr. Mar has nothing to disclose. Dr. Mednick has nothing to disclose. Dr. Banwell has received personal compensation for activities with Novartis. Dr. Banwell has received personal compensation in an editorial capacity for Multiple Sclerosis and Related Disorders. Dr. Alper has nothing to disclose. Dr. Graves has received research support from Genentech, Biogen and S3 Group. Dr. Lotze has nothing to disclose. Dr. Tillema has nothing to disclose. Dr. Rensel has received personal compensation for activities with Novartis, Genzyme, and Teva as an advisory board member or speaker. Dr. Rensel has received research support from the National Multiple Sclerosis Society and Genzyme. Dr. Gorman has nothing to disclose. Dr. Ness has received research support from Novartis Pharmaceuticals. Dr. Waldman has received royalty payments from UpToDate. Dr. Schreiner has received personal compensation for activities wi...

Source: Neurology - April 17, 2017 Category: Neurology Authors: Schwarz, C., Grover, S., Powell, V., Noguera, A., Mah, J., Mar, S., Mednick, L., Banwell, B., Alper, G., Graves, J., Lotze, T., Tillema, J.-M., Rensel, M., Gorman, M., Ness, J., Waldman, A., Schreiner, T., Waubant, E., Yeh, E. A. Tags: Pediatric Multiple Sclerosis Source Type: research