Interleukin-37 is Elevated in Acute Ischemic Stroke (P1.260)

Conclusions:The study shows a rather stable elevation of IL-37 levels post-ischemic stroke, which if compared to available data from other studies, is 3–10 times elevated after acute ischemic stroke with an uptrend in the first few days. IL-37 plays some role in mediating post-stroke inflammation with significant rise in serum and urine IL- 37 levels suggesting a key role of this novel cytokine in post-stroke pathology.Disclosure: Dr. Bushnaq has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Duraisamy has nothing to disclose. Dr. Tasneem has nothing to disclose. Dr. Khan has nothing to disclose. Dr. Leira has nothing to disclose. Dr. Zaheer has nothing to disclose.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Bushnaq, S., Zafar, A., Duraisamy, K., Tasneem, N., Khan, M., Leira, E., Zaheer, A. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research