Lupus nephritis: CD11b suppresses inflammation in SLE
Nature Reviews Nephrology 13, 262 (2017).
doi:10.1038/nrneph.2017.50
Author: Shimona Starling
Single-nucleotide polymorphisms (SNPs) in the ITGAM gene (which encodes the adhesion molecule CD11b) are associated with an increased risk of systemic lupus erythematosus (SLE). Faridi et al. show that ITGAM SNPs that reduce CD11b function correlate with elevated activity of pro-inflammatory
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Shimona Starling Tags: Research Highlight Source Type: research