Activation of Nrf2-Antioxidant Signaling by 1,25-Dihydroxycholecalciferol Prevents Leptin-Induced Oxidative Stress and Inflammation in Human Endothelial Cells [Biochemical, Molecular, and Genetic Mechanisms]

Conclusion: Pretreatment with 1,25(OH)2D3 in the presence of a high concentration of leptin has a beneficial effect on HUVECs through the regulation of mediators of antioxidant activity and inflammation.

Source: Journal of Nutrition - April 3, 2017 Category: Nutrition Authors: Teixeira, T. M., da Costa, D. C., Resende, A. C., Soulage, C. O., Bezerra, F. F., Daleprane, J. B. Tags: Obesity and Metabolism Research Articles Biochemical, Molecular, and Genetic Mechanisms Source Type: research