Risk of Serious Infection in Juvenile Idiopathic Arthritis Patients Associated With Tumor Necrosis Factor Inhibitors and Disease Activity in the German Biologics in Pediatric Rheumatology Registry
ConclusionThe total rate of serious infections reported in the BIKER registry seems low. Treatment with etanercept or adalimumab increases the risk for serious infection slightly, compared to methotrexate. Disease activity expressed by cJADAS10 appears to be an independent risk factor.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Ingrid Becker, Gerd Horneff Tags: Pediatric Rheumatology Source Type: research
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