Inhibition of JNK by pi class of glutathione S-transferase through PKA/CREB pathway is associated with carnosic acid protection against 6-hydroxydopamine-induced apoptosis.

CONCLUSION: CA prevents 6-OHDA-induced apoptosis via inhibition of JNK by GSTP through the PKA/CREB pathway.
PMID: 28288932 [PubMed - as supplied by publisher]

Source: Food and Chemical Toxicology - March 9, 2017 Category: Food Science Authors: Lin CY, Fu RH, Chou RH, Chen JH, Wu CR, Chang SW, Tsai CW Tags: Food Chem Toxicol Source Type: research