[Investigation of seropositivity of Bordetella pertussis in adults in a university hospital].

[Investigation of seropositivity of Bordetella pertussis in adults in a university hospital]. Mikrobiyol Bul. 2017 Jan;51(1):62-72 Authors: Öksüz L, Gürler N, Ağaçfidan A Abstract Whooping cough is a vaccine-preventable infectious diseases caused by Bordetella pertussis/parapertussis. Despite of routine immunization programs in the world, pertussis still remains endemic. Recently unvaccinated or partially immunized infants have infected with this pathogen and also increase of incidence was observed in adolescents and adults. The source of pertussis in newborns are attributed to household, especially due to the family members. Theaim of this study was to determine B.pertussis IgG antibody positivity by ELISA method in adults. Eighty-four of the total study population (39.6%) were anti-pertussis IgG positive, 128 (60.4%) were negative. The samples included in the study (n= 212) were divided into three groups according to ages: 19-35 years (Group 1, n= 61), 36-50 years (Group 2, n= 58), 51-65 years (Group 3, n= 93). Anti-pertussis IgG antibody positivity was 26.2% (n= 22) in Group 1, 26.2% (n= 22) in Group 2 and 47.6% (n= 40) in Group 3. According to the anti-pertussis IgG positivity results, no significant difference was observed between genders. The results were obtained as absorbance values by ELISA test, then transformed into semi-quantitative values as NovaTec Test Unit (NTU). NTU positive values were between 11.01-39.4. Ninet...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research