Ten million lives saved by 1962 breakthrough, study says
Nearly 200 million cases of polio, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A -- and approximately 450,000 deaths from these diseases -- were prevented in the US alone between 1963 and 2015 by vaccination, researchers estimate.
Authors: Bellan M, Sainaghi PP, Minh MT, Minisini R, Molinari L, Baldrighi M, Salmi L, Barbaglia MN, Castello LM, Ravanini P, Avanzi GC, Pirisi M Abstract AIM: Plasma Gas6 was tested as an alternative to Baveno VI criteria (liver stiffness 150 × 109/l) in an endoscopy-sparing strategy. METHODS: A total of 160 patients with chronic hepatitis C and advanced fibrosis/cirrhosis underwent, on the same occasion, liver elastography, upper endoscopy, a platelet count and serum Gas6 measurement Results: A total of 74/160 (46%) patients had esophageal varices, that were small (diameter
A promising vaccine for dengue fever is in limbo after the Philippines suspended its use amid widespread public anger and fears about its safety.
In this article, we take a look at how long the hepatitis C virus can survive outside the body, and how this impacts on transmission risks.
A co-ordinated approach to vaccination is stopping the disease spreading in Nepal
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Publication date: Available online 16 December 2017 Source:Microbial Pathogenesis Author(s): O. Kerro Dego, R.A. Almeida, A.M. Saxton, R.D. Abdi, D.B. Ensermu, S.P. Oliver In spite of the increasing prevalence of Streptococcus uberis mastitis, its pathogenesis and associated virulence factors are not clearly defined. The aim of this study was to identify virulence associated genes and their products that can be used to develop effective vaccine to control bovine S. uberis mastitis. S. uberis was co-cultured with primary bovine mammary epithelial cells (PBMEC) or infused into mammary gland of dairy cows. The messenger RNA ...
CONCLUSION: Primary care services should be reorganized and integrated with public health services. PMID: 29243549 [PubMed - as supplied by publisher]
Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody against Zika virus. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”></span> Click arrow to play Download Immune 3 (48 MB .mp3, 79 min) Subscribe (free): iTunes, RSS, email Become a patron of Immune!
Authors: Sugawara Y, Hibi T Abstract Chronic hepatitis C virus (HCV) infection remains a widespread public health concern and many people are infected with HCV. HCV is one of the leading indications for liver transplantation. Direct-acting antiviral agents (DAAs) against HCV have changed the course of chronic HCV infection, however, making it a curable disease. DAA treatment may be initiated before or after liver transplantation. In the present review, we present the available data on DAA treatment of HCV in liver transplant recipients. PMID: 29238003 [PubMed - as supplied by publisher]
Abstract Beginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks caused by CHIKV have continued and expanded, serious consideration must be given to identifying potential options for vaccines and therapeutics. Currently, there are no licensed products in this realm, and control relies completely on the use of personal protective measures and integrated vector control, which are only minimally effective. Therefore, it is prudent to urgently examine further possibilities for control. Vaccines have ...