Ten million lives saved by 1962 breakthrough, study says
(University of Illinois at Chicago) Nearly 200 million cases of polio, measles, mumps, rubella, varicella, adenovirus, rabies and hepatitis A -- and approximately 450,000 deaths from these diseases -- were prevented in the US alone between 1963 and 2015 by vaccination, researchers estimate. The study is published in AIMS Public Health.
AbstractObjectiveTo assess prospectively the maternal and fetal outcome among pregnant women with chronic Hepatitis-C virus (HCV) infection compared to normal control group.MethodsA prospective observational study conducted on 342 pregnant women with HCV who were divided into two groups according to polymerase chain reaction (PCR) result, group 1 (n = 184, HCV-PCR negative) and group 2 (n = 154, HCV-PCR positive) with a third group of normal pregnant women (n = 170). Obstetric outcome was recorded.ResultsPatients with positive HCV-PCR have more elevated liver enzymes (p
Abstract A minority of injecting drug users, termed exposed uninfected, are resistant to hepatitis C (HCV) infection despite repeated low‐dose exposures. We identify for the first time a cohort of blood recipients who remained uninfected despite large‐dose exposure to HCV‐contaminated blood and characterise immune factors that may confer protection. Of 1340 blood recipients from the English Look Back database who were transfused HCV‐contaminated blood, we identified 8 who remained uninfected. In these 8 exposed uninfecteds, we characterised their natural killer (NK) cell populations and HCV‐specific T cell respon...
[Daily Trust] The World Health Organization (WHO) has said 13,502 children have rejected being administered polio vaccine in Potiskum Local Government Area of Yobe State after a rumour of 'killer injection' circulated in Yobe State.
Carmen W. E. Embregts, Dimitri Rigaudeau, Tom áš Veselý, Dagmar Pokorová, Niels Lorenzen, Jules Petit, Armel Houel, Malte Dauber, Heike Schütze, Pierre Boudinot, Geert F. Wiegertjes, Maria Forlenza
CONCLUSION: Long-term, low-dose exposure to MC-LR is unlikely to lead to chronic liver disease in the setting of a normal liver or exacerbate existing liver disease in the setting of ongoing hepatitis. PMID: 29055933 [PubMed - in process]
CONCLUSIONS: The present digital imaging analysis technique is reproducible and available worldwide, allowing its use in clinical practice, and can be considered as a complementary tool to traditional histological methods. PMID: 29055926 [PubMed - in process]
CONCLUSIONS: PEG-interferon α-2a and PEG-interferon α-2b are effective antiviral drugs for the treatment of HbeAgpositive CHB, which has a HBsAg seroconversion rate of more than 5%. Furthermore, this sustained response effect was maintained at the 24th and 48th week of follow-up after withdrawal. PMID: 29055925 [PubMed - in process]
CONCLUSIONS: Our developed score can not only help to assess liver fibrosis staging effectively but also avoid the invasiveness and the limitations of liver biopsy in Egyptian hepatitis C virus patients. PMID: 29055924 [PubMed - in process]
CONCLUSION: Our TM program engages and retains a population that faces many barriers to effective HCV treatment. TM patients initiated HCV therapy and achieved High SVR rates comparable to those obtained using traditional models of care. PMID: 29055923 [PubMed - in process]
CONCLUSIONS: Clinical trials are under way to assess whether the clearance of HCV RNA from serum by direct-acting antiviral drugs reduces all cause or disease-specific (cardiovascular) mortality among patients on maintenance dialysis. PMID: 29055921 [PubMed - in process]