Canstatin stimulates migration of rat cardiac fibroblasts via secretion of matrix metalloproteinase-2

In conclusion, this study revealed a novel function of canstatin for inducing cell migration of adult rat cardiac fibroblasts at least in part by ERK phosphorylation through MMP-2 secretion, possibly via actin cytoskeletal change.

Source: AJP: Cell Physiology - February 28, 2017 Category: Cytology Authors: Okada, M., Murata, N., Yamawaki, H. Tags: RESEARCH ARTICLE Source Type: research