Popular heartburn drugs linked to gradual yet'silent' kidney damage

The sudden onset of kidney problems often serves as a warning for doctors to discontinue patients'use of proton pump inhibitors (PPIs), sold under brand names Prevacid, Prilosec, Nexium and Protonix, among others. But a new study indicates that more than half of patients who develop chronic kidney damage while taking the drugs don't experience acute kidney problems beforehand, according to researchers.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Authors: Luo Z, Hu X, Chen C, Zhu L, Zhang W, Shen Y, He J Abstract Objective: To observe the influence of the catgut-embedding method in Du Meridian acupoint on the mental and psychological state of patients with gastroesophageal reflux disease (GERD) and analyze its possible mechanism. Methods: According to the random number table, 60 patients with GERD were randomly divided into groups of acupoint catgut embedding and Western medicine, 30 cases in each group. The acupoint group was given catgut embedment in the positive reaction points along the Du Meridian, while the Western medicine group received lansopra...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
While sick with COVID-19, President Trump is taking an antacid. Doctors have been exploring whether these medicines can treat SARS-CoV-2 infections, and the results are mixed.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
Title: Heartburn Meds Tied to Higher Diabetes RiskCategory: Health NewsCreated: 10/2/2020 12:00:00 AMLast Editorial Review: 10/5/2020 12:00:00 AM
Source: MedicineNet Diabetes General - Category: Endocrinology Source Type: news
President ’s doctor reveals treatment with experimental antibody cocktail REGN-COV2Coronavirus – latest updatesSee all our coronavirus coverageDonald Trump is being treated with an experimental antibody drug that has shown promising initial early results but has yet to be peer-reviewed. According to statement from his doctor, the president has received a single eight-gram dose of anantibody cocktail called REGN-COV2– a combination of two human neutralising antibodies against the virus.The treatment was developed by Regeneron Pharmaceuticals, which previously developed a similar antibody drug against Ebola...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Donald Trump Coronavirus outbreak US news Infectious diseases Microbiology Medical research Science Source Type: news
U.S. President Donald Trump has received a promising but experimental COVID-19 drug still in clinical trials, according to a White House statement released Friday afternoon, following his diagnosis with the disease. Sean Conley, the President’s personal physician, wrote in a memo that he treated Trump with an eight-gram dose of Regeneron’s experimental antibody cocktail. Trump has also received zinc, vitamin D, aspirin, melatonin and a heartburn drug thought to help fight COVID-19. An update from President @realDonaldTrump's physician: pic.twitter.com/cTsXO4Df6b — Kayleigh McEnany (@PressSec) Octobe...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
FRIDAY, Oct. 2, 2020 -- Often-used drugs called proton pump inhibitors (PPIs) ease heartburn symptoms, but a new study suggests they might also increase the risk of type 2 diabetes. Chinese researchers drew on information from studies of more than...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusions: Esophageal involvement among South Koreans with SSc was characterized by heterogeneous motility patterns, with a higher prevalence of normal motility and lower prevalence of erosive esophagitis. Reflux hypersensitivity or functional heartburn might be partly attributed to the perception of esophageal symptoms in SSc patients who have neither gastroesophageal reflux disease nor esophageal dysmotility. PMID: 32989185 [PubMed]
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
Authors: Bhatia S, Pareek KK, Kumar A, Upadhyay R, Tiwaskar M, Jain A, Gupta P, Nadkar MY, Prakash A, Dutta A, Chavan R, Kedia S, Ahuja V, Ghoshal U, Agarwal A, Makharia G Abstract Gastroesophageal reflux disease (GERD) is a common problem in the community. The Indian Society of Gastroenterology and Association of Physicians of India have developed this evidence-based practice guideline for management of GERD in adults. A modified Delphi process was used to develop this consensus containing 43 statements, which were generated by electronic voting iteration as well as face-to-face meeting, and review of the supporti...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
A 61-year-old man woke up with unusual heartburn (no radiation or dyspnea) and drove himself to the Emergency Department. He looked comfortable with normal physical examination and ECG. Blood pressure was 110/60 mm/Hg (both hands), heart rate 54/min, respiratory rate 12/min, oxygen saturation 98%. He had hypertension (well-controlled on nifedipine 30 mg/atenolol 100 mg), obesity, smoked 1pack/day, and took non-steroidal anti-inflammatory drugs (NSAIDs) over 5 days for knee pain. Hb was 14.1 g/dL, white blood cell count 12.9  × 103/µL, platelets 223 × 103/µL, C-reactive protein 16.8 mg/L, blo...
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to The Editor Source Type: research
This study examined the predictive role of the endoscopic findings, including the flap valve grade for pathologic acid exposure (PAE) to establish an endoscopic prediction model in patients with neither reflux esophagitis nor HH. Methods: Five hundred seventy-eight patients who underwent upper endoscopy and 24 hours pH monitoring for reflux esophageal symptoms without evidence of reflux esophagitis and HH were analyzed. The gastroesophageal flap valve (GEFV), esophageal metaplasia, and chronic atrophic gastritis were assessed. The association between the endoscopic parameters and PAE was evaluated. Results: Four ...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
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