Fate of Salmonella Senftenberg in broiler chickens evaluated by challenge experiments.

Fate of Salmonella Senftenberg in broiler chickens evaluated by challenge experiments. Avian Pathol. 2014 May 13;:1-16 Authors: Kallapura G, Kogut MH, Morgan MJ, Pumford NR, Bielke LR, Wolfenden AD, Faulkner OB, Latorre JD, Menconi A, Hernandez-Velasco X, Kuttappan VA, Hargis BM, Tellez G Abstract Experimental and epidemiological evidence have indicated the respiratory route to be a potential portal of entry for salmonellae in poultry. The purpose of this study was to evaluate and compare the infectivity of Salmonella enterica serovar Senftenberg following oral gavage (OR), intratracheal (IT) or intravenous (IV) challenge in chickens. Seven-day-old chicks were challenged with either 104 or 106 CFU of S. Senftenberg /chick, OR, IT or IV, respectively in two independent trials. Chickens were humanely killed 24 h post challenge and S. Senftenberg was cultured and enumerated from cecal contents, ceca-cecal tonsils and liver and spleen (LS). In both trials, IT delivery of S. Senftenberg was the only route that allowed colonization of the ceca of the chickens when compared with OR or IV challenge in a dose response fashion (P < 0.05). Low levels of S. Senftenberg recovery from selectively enriched LS samples were found only after high dose administration of S. Senftenberg by either route in both trials. The results of the present study suggest that S. Senftenberg entering the blood is likely to be cleared and will not be able to coloniz...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research