Numerical and experimental investigations of the flow –pressure relation in multiple sequential stenoses coronary artery

This study investigates the flow –pressure relation in an idealised multiple sequential stenoses coronary artery model via numerical and experimental approaches. Pressure drop is linearly correlated with flow rate irrespective of the number of stenosis. Computational fluid dynamics results are in good agreement with the experimen tal data, demonstrating reasonable accuracy of vFFR. It was also found that the difference between data obtained with steady and pulsatile flows is negligible, indicating the steady flow may be used instead of pulsatile flow conditions in vFFR computation. This study adds to the current understandin g of vFFR and may improve its clinical applicability as an adjunct to invasively determined FFR.
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research