Use of Lactated Ringer ’s solution does not eliminate the risk of strong ion difference-related metabolic acidosis following on-pump cardiac surgery.

In conclusion, our data confirm that there is a direct correlation between a strong ion difference and base excess following on-pump cardiac surgery. The use of RL prevented significant hyperchloraemia, but did not eliminate the risk of strong ion difference-related metabolic acidosis. The change in the strong ion difference was primarily linked to perioperative changes in the serum sodium concentration. PMID: 28078858 [PubMed - in process]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research