In vitro study of normoxic epidermal growth factor (EGF)‐induced HIF‐1α, VEGF and BNIP3 expression in head and neck squamous cell carcinoma cell lines: implications for anti‐EGFR therapy

Conclusions
The search for molecular predictors of sensitivity to gefitinib in HNSCC should be extended to the activation status of EGFR‐downstream pathways, pAkt, pMAPK, and HIF‐1α. Head Neck, 2014

Source: Head and Neck - May 2, 2014 Category: ENT & OMF Authors: Pablo Secades, Inés Saenz de Santamaría, Anna Merlo, Carlos Suarez, María‐Dolores Chiara Tags: Original Article Source Type: research