Therapeutic mechanisms of ibuprofen, prednisone and betamethasone in osteoarthritis.

In conclusion, prednisone, ibuprofen and betamethasone may prevent OA by suppressing the expression of IL‑6 and IL‑8, subsequently inactivating NF‑κB and STAT3 pathways, and ultimately, leading to decreased levels of collagen I, MMP‑1, and MMP‑13. PMID: 28035387 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28035387?dopt=Abstract

Source: Molecular Medicine Reports - January 1, 2017 Category: Molecular Biology Tags: Mol Med Rep Source Type: research